Thesis (Ph.D.)-University of Birmingham, Dept. of Biochemistry.
Myosin Light Chain Myosin Light Chain Kinase Sedimentation Equilibrium Sucrose Density Gradient Centrifugation Transfer Natural These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm :// Myosin light‐chain kinase (MLCK) regulates actin‐myosin II interactions in nonskeletal muscle cells, and the use of specific pharmacological inhibitors has implicated MLCK in retinal growth cone moti (SICI)() Migration Inhibition Factor Myosin Light Chain Myosin Light Chain Kinase Regulatory Light Chain TRPC5 Channel These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm :// Jianghui Hou, in The Paracellular Channel, Myosin Light Chain Kinase. Myosin light chain kinase (MLCK), which induces contraction of the perijunctional actomyosin ring through myosin II regulatory light chain phosphorylation, has emerged as a key regulator of the paracellular channel permeability. When the MDCK cells were transfected with an active form of MLCK, the paracellular /myosin-light-chain-kinase.
Role of myosin light chain kinase and RhoGTPases. Myosin light chain kinase (MLCK) is a Ca 2+ –CaM-dependent enzyme that phosphorylates MLC at Ser or Ser/Thr (Dudek and Garcia, ; Lazar and Garcia, ; Verin et al., a,b; Wadgaonkar et al., ). This phosphorylation promotes actin–myosin cross-bridging that leads to 购买Myosin light chain kinase/MLCK兔多克隆抗体(ab)，Myosin light chain kinase/MLCK抗体经WB验证，可与小鼠,兔样本反应。2篇文献引用，1个独立用户反馈。 Myosin light chain kinase (MLCK) and Rho-associated coiled-coil containing protein kinase (ROCK) have been shown to utilize phosphorylation of MLC-2 as a mechanism to regulate the AJC in various forms of intestinal mucosal injury [7,8,9,10,15,16,17]. However, the mechanistic role of MLCK and ROCK in the regulation of AJC, including TJs and AJs Takashima, S. () Phosphorylation of myosin regulatory light chain by myosin light chain kinase, and muscle contraction, Circ. J., 73, – PubMed CrossRef Google Scholar
购买Myosin light chain kinase/MLCK兔多克隆抗体(ab)，Myosin light chain kinase/MLCK抗体经IHC-P验证，可与人,小鼠,大鼠样本反应。3个独立用户反馈。 Myosin light chain kinase regulates intestinal permeability of mucosal homeostasis in Crohn’s disease. Expert Review of Clinical Immunology. Accepted 10 November Upstream Regulators. Protein kinase C and ROC Kinase are involved in regulating Calcium ion intake; these Calcium ions, in turn stimulate a MYLK, forcing a contraction. Rho kinase also modulates the activity of MYLK by downregulating the activity of MYLK's counterpart protein: Myosin Light Chain Phosphatase (MYLP). In addition to downregulation of MYLK, ROCK indirectly strengthens actin/myosin ML-7, a myosin light chain kinase (MLCK) inhibitor, prevented cell-to-cell spread of Shigella but not another intracellular pathogen, Listeria monocytogenes. In a later study, TER was shown to drop 70% by 90 min following infection with S. flexneri regardless of whether an invasive or noninvasive strain was used. Invasive Shigella /myosin-light-chain-kinase-inhibitor.